I honestly don't think I can answer this one. As a long time TV fanatic I have so many favorites.... Favorite Drama of all time? The West Wing. Favorite Comedy? Seinfeld of course. Favorite current show? Grey's, Glee, Deadliest Catch, and all the Law and Orders. I guess if I was pressed to pick one show I guess I'd have to go with Friends. Even though I've seen every episode a million times I can still watch it and laugh.